English papers

The use of very high-doses of baclofen for the treatment of alcohol-dependence: a case series

Post Views: 498 Renaud de Beaurepaire Groupe Hospitalier Paul-Guiraud, Villejuif, France Baclofen, particularly high-dose baclofen, has recently emerged as a treatment of major interest for alcohol-dependence. However, baclofen has many potentially dangerous side effects, and the maximal dose of baclofen…
Savoir plus

Nipping Cue Reactivity in the Bud: Baclofen Prevents Limbic Activation Elicited by Subliminal Drug Cues

Post Views: 663 The Journal of Neuroscience, 2 April 2014, 34(14): 5038-5043; doi: 10.1523/JNEUROSCI.4977-13.2014 Abstract Relapse is a widely recognized and difficult to treat feature of the addictions. Substantial evidence implicates cue-triggered activation of the mesolimbic dopamine system as an…
Savoir plus

Off-Label Baclofen Prescribing Practices among French Alcohol Specialists: Results of a National Online Survey

Post Views: 3 067 Benjamin Rolland1,2*, François Paille1,3, Benoit Fleury1,4, Olivier Cottencin1,2, Amine Benyamina1,5, Henri-Jean Aubin1,5 1 Société Française d’Alcoologie, Issy-les-Moulineaux, France, 2 Service d’Addictologie, CHU Lille, Univ Lille Nord de France, Lille, France, 3 Service d’Addictologie, CHU Nancy, Université ,…
Savoir plus

Abstinence and ‘Low-Risk’ Consumption 1 Year after the Initiation of High-Dose Baclofen: A Retrospective Study among ‘High-Risk’ Drinkers

Post Views: 277 Laurent Rigal, Constance Alexandre-Dubroeucq, Renaud de Beaurepaire2, Claire Le Jeunne and Philippe Jaury – Alcohol and Alcoholism Advance Access published March 19, 2012 Abstract — Aims: The aim of the study was to assess the proportions of ‘high-risk’…
Savoir plus