Olivier Ameisen – Alcohol & Alcoholism Vol. 42, No. 5, p. 506, 2007
I wish to propose a hypothesis that could help explain some of the effects of baclofen in alcohol dependence that are described in Dr. Bucknam’s case study (Bucknam, 2007) and in my self-case report (Ameisen, 2005). At a behavioural level, alcohol, baclofen and GHB all share sedative/hypnotic effects in humans. Clinical trials have shown baclofen to reduce anxiety in alcoholic (Krupitsky et al ., 1993; Addolorato et al ., 2002) and non-alcoholic (Breslow et al ., 1989; Drake et al ., 2003) patients alike.
GHB deficiency in alcohol dependance
Déficience en GHB dans l’alcoolo-dépendance
baclofene, baclofen,arreter de boire, stopper l’alcool, en finir avec l’alcool, baclofene, baclofen, baclophen, sortir de l’alcoolisme, dépendance, médicament pour arreter de boire, traitement alcoolisme, je veux arreter de boire,alcool, alcoolisme, déni alcoolique, craving, arret alcool